Aminoacyltransferase

Aminoacyltransferases (EC 2.3.2) are acyltransferase enzymes which act upon an amino group. For instance, aminoacyl tRNA synthetases attach an aminoacid through esterification to the corresponding tRNA. The activation of amino acids it aminoacyl-tRNA synthetase requires hydrolysis of ATP to AMP plus PP_i. The aminoacyl-tRNA molecule has close relationships with elongation facts like EF-Tu.

Peptidyl transferases are also a type of aminoacyltransferase that catalyze the formation of peptide bonds, as well as the hydrolytic step that leads to the release of newly synthesized proteins off the tRNA.

External links

Aminoacyltransferases at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Transferases: acyltransferases (EC 2.3)

2.3.1: other than amino-acyl groups

acetyltransferases: Acetyl-Coenzyme A acetyltransferase
N-Acetylglutamate synthase
Choline acetyltransferase
Dihydrolipoyl transacetylase
Acetyl-CoA C-acyltransferase
Beta-galactoside transacetylase
Chloramphenicol acetyltransferase
N-acetyltransferase
Histone acetyltransferase
- P300/CBP
- NAT2

2.3.2: Aminoacyltransferases

2.3.3: converted into alkyl on transfer

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)