BAT4

Protein-coding gene in the species Homo sapiens
GPANK1
Identifiers
AliasesGPANK1, ANKRD59, BAT4, D6S54E, G5, GPATCH10, G-patch domain and ankyrin repeats 1
External IDsOMIM: 142610; MGI: 2148975; HomoloGene: 13035; GeneCards: GPANK1; OMA:GPANK1 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for GPANK1
Genomic location for GPANK1
Band6p21.33Start31,661,228 bp[1]
End31,666,283 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for GPANK1
Genomic location for GPANK1
Band17 B1|17 18.59 cMStart35,340,431 bp[2]
End35,343,790 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • left testis

  • right testis

  • apex of heart

  • blood

  • sural nerve

  • gastrocnemius muscle

  • gonad

  • Achilles tendon

  • left ventricle

  • muscle of thigh
Top expressed in
  • epithelium of small intestine

  • intestinal villus

  • Ileal epithelium

  • spermatid

  • granulocyte

  • bone marrow

  • inferior colliculus

  • spermatocyte

  • superior colliculus

  • testicle
More reference expression data
BioGPS
n/a
Orthologs
SpeciesHumanMouse
Entrez

7918

81845

Ensembl
ENSG00000236011
ENSG00000206408
ENSG00000204438
ENSG00000223932
ENSG00000228605

ENSG00000232312
ENSG00000233210

ENSMUSG00000092417

UniProt

O95872

Q61858

RefSeq (mRNA)

NM_001199237
NM_001199238
NM_001199239
NM_001199240
NM_033177

NM_001128597
NM_032460

RefSeq (protein)

NP_001186166
NP_001186167
NP_001186168
NP_001186169
NP_149417

NP_001122069
NP_115849

Location (UCSC)Chr 6: 31.66 – 31.67 MbChr 17: 35.34 – 35.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein BAT4 is a protein that in humans is encoded by the BAT4 gene.[5][6][7]

A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. The protein encoded by this gene is thought to be involved in some aspects of immunity.[7]

References

  1. ^ a b c ENSG00000206408, ENSG00000204438, ENSG00000223932, ENSG00000228605, ENSG00000232312, ENSG00000233210 GRCh38: Ensembl release 89: ENSG00000236011, ENSG00000206408, ENSG00000204438, ENSG00000223932, ENSG00000228605, ENSG00000232312, ENSG00000233210 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000092417 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Spies T, Blanck G, Bresnahan M, Sands J, Strominger JL (Feb 1989). "A new cluster of genes within the human major histocompatibility complex". Science. 243 (4888): 214–7. Bibcode:1989Sci...243..214S. doi:10.1126/science.2911734. PMID 2911734.
  6. ^ Spies T, Bresnahan M, Strominger JL (Dec 1989). "Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B". Proc Natl Acad Sci U S A. 86 (22): 8955–8. Bibcode:1989PNAS...86.8955S. doi:10.1073/pnas.86.22.8955. PMC 298409. PMID 2813433.
  7. ^ a b "Entrez Gene: BAT4 HLA-B associated transcript 4".

External links

Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Xie T, Rowen L, Aguado B, et al. (2004). "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse". Genome Res. 13 (12): 2621–36. doi:10.1101/gr.1736803. PMC 403804. PMID 14656967.
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.


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