Estradiol hemisuccinate
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Trade names | Eutocol, Hosterona (with progesterone) |
Other names | Estradiol succinate; Estradiol 17β-hemisuccinate; Estradiol 17β-succinate |
Routes of administration | By mouth, intramuscular injection |
Drug class | Estrogen; Estrogen ester |
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ECHA InfoCard | 100.163.857 |
Chemical and physical data | |
Formula | C22H28O5 |
Molar mass | 372.461 g·mol−1 |
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Estradiol hemisuccinate (brand name Eutocol), or simply estradiol succinate, also known as estradiol 17β-hemisuccinate, is an estrogen medication and an estrogen ester – specifically, the hemisuccinate ester of estradiol.[1] It is used as a component of hormone replacement therapy for menopause.[2] Like other estrogens, estradiol hemisuccinate has been found to have beneficial effects on the skin, with improvement of skin thickness observed.[2][3]
Estradiol hemisuccinate is also a component of estradiol hemisuccinate/progesterone (brand name Hosterona), an injectable preparation used to induce withdrawal bleeding in women with amenorrhea.[4][5][6]
See also
References
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 897. ISBN 978-1-4757-2085-3.
- ^ a b Thompson Z, Maibach HI (2010). "Biological Effects of Estrogen on Skin". In Farage MA, Miller KW (eds.). Textbook of Aging Skin. pp. 361–367 (362). doi:10.1007/978-3-540-89656-2_35. ISBN 978-3-540-89655-5.
- ^ Maheux R, Naud F, Rioux M, Grenier R, Lemay A, Guy J, Langevin M (February 1994). "A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness". American Journal of Obstetrics and Gynecology. 170 (2): 642–649. doi:10.1016/s0002-9378(94)70242-x. PMID 8116726.
- ^ "¿Qué es Hosterona y para qué sirve?" [What is Hosterona and what is it for?]. matchmyrx.com (in Spanish). PRX Control Solutions. Archived from the original on 13 April 2019.
- ^ "Hosterona - Para qué sirve" [Hosterona - What it is for]. Los Medicamentos (in Spanish). 23 November 2012.
- ^ "HOSTERONA (Hormonoterapia)". Laboratorio GADOR.
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- Estradiol (as a hormone)
- Estradiol (as a medication)
- Pharmacodynamics of estradiol
- Pharmacokinetics of estradiol
- Estrogen (as a hormone)
- Estrogen (as a medication)
- Menopausal hormone therapy
- Feminizing hormone therapy
- Estradiol-containing birth control pill
- Combined injectable birth control
- High-dose estrogen
- Hydroxylation of estradiol
- Estradiol acetate
- Estradiol acetylsalicylate
- Estradiol anthranilate
- Estradiol benzoate butyrate
- Estradiol benzoate cyclooctenyl ether
- Estradiol benzoate
- Estradiol butyrylacetate
- Estradiol cyclooctyl acetate
- Estradiol cypionate
- Estradiol decanoate
- Estradiol diacetate
- Estradiol dibutyrate
- Estradiol dienantate
- Estradiol dipropionate
- Estradiol distearate
- Estradiol disulfate
- Estradiol diundecylate
- Estradiol diundecylenate
- Estradiol enantate
- Estradiol furoate
- Estradiol glucuronide
- Estradiol hemisuccinate
- Estradiol hexahydrobenzoate
- Estradiol monopropionate
- Estradiol mustard
- Estradiol palmitate
- Estradiol phenylpropionate
- Estradiol phosphate
- Estradiol pivalate
- Estradiol propoxyphenylpropionate
- Estradiol salicylate
- Estradiol stearate
- Estradiol sulfamate
- Estradiol sulfate
- Estradiol undecylate
- Estradiol undecylenate
- Estradiol valerate
- Estramustine phosphate (estradiol normustine phosphate)
- Estrogen ester
- Polyestradiol phosphate
- Estrone
- Estriol
- Estetrol
- Ethinylestradiol
- Conjugated estrogens
- Esterified estrogens
- Estrone sulfate
- Estropipate (piperazine estrone sulfate)
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