SH3PXD2A |
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![](//upload.wikimedia.org/wikipedia/commons/thumb/8/80/Protein_SH3PXD2A_PDB_2DNU.png/250px-Protein_SH3PXD2A_PDB_2DNU.png) |
Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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2DNU, 2EGA, 2EGC, 2EKH |
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Identifiers |
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Aliases | SH3PXD2A, FISH, SH3MD1, TKS5, SH3 and PX domains 2A |
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External IDs | MGI: 1298393; HomoloGene: 7317; GeneCards: SH3PXD2A; OMA:SH3PXD2A - orthologs |
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Gene location (Human) |
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![Chromosome 10 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/2/2f/Ideogram_human_chromosome_10.svg/300px-Ideogram_human_chromosome_10.svg.png) | Chr. | Chromosome 10 (human)[1] |
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| Band | 10q24.33 | Start | 103,594,027 bp[1] |
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End | 103,855,543 bp[1] |
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Gene location (Mouse) |
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![Chromosome 19 (mouse)](//upload.wikimedia.org/wikipedia/commons/thumb/8/82/Ideogram_house_mouse_chromosome_19.svg/260px-Ideogram_house_mouse_chromosome_19.svg.png) | Chr. | Chromosome 19 (mouse)[2] |
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| Band | 19|19 C3 | Start | 47,248,613 bp[2] |
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End | 47,452,840 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - cervix
- sural nerve
- trigeminal ganglion
- tibia
- inferior ganglion of vagus nerve
- myometrium
- vagina
- cecum
- tendon
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| Top expressed in | - molar
- gastrula
- ascending aorta
- sciatic nerve
- aortic valve
- body of femur
- belly cord
- calvaria
- skin of abdomen
- utricle
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| More reference expression data |
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BioGPS | ![](//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PBB_GE_SH3PXD2A_207661_s_at_fs.png/250px-PBB_GE_SH3PXD2A_207661_s_at_fs.png)
![](//upload.wikimedia.org/wikipedia/commons/thumb/d/d6/PBB_GE_SH3PXD2A_213252_at_fs.png/250px-PBB_GE_SH3PXD2A_213252_at_fs.png) | More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- superoxide-generating NADPH oxidase activator activity
- phosphatidylinositol binding
- protease binding
- phosphatidylinositol-4,5-bisphosphate binding
- phosphatidylinositol-5-phosphate binding
- phosphatidylinositol-3-phosphate binding
- phosphatidylinositol-3,4-bisphosphate binding
- phosphatidylinositol-4-phosphate binding
| Cellular component | - cytoplasm
- podosome
- cell junction
- cell projection
- cytosol
| Biological process | - osteoclast fusion
- superoxide metabolic process
- reactive oxygen species metabolic process
- positive regulation of catalytic activity
- podosome assembly
- extracellular matrix organization
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_001164717 NM_008018 NM_177833 |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 10: 103.59 – 103.86 Mb | Chr 19: 47.25 – 47.45 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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