VM (nerve agent)

VM
Skeletal formula of VM
Ball-and-stick model of VM
Names
Preferred IUPAC name
S-[2-(Diethylamino)ethyl] O-ethyl methylphosphonothioate
Identifiers
CAS Number
  • 21770-86-5 ☒N
3D model (JSmol)
  • Interactive image
ChemSpider
  • 28577 checkY
PubChem CID
  • 30800
UNII
  • 2XM5EU7NUM checkY
CompTox Dashboard (EPA)
  • DTXSID40865014 Edit this at Wikidata
InChI
  • InChI=1S/C9H22NO2PS/c1-5-10(6-2)8-9-14-13(4,11)12-7-3/h5-9H2,1-4H3 checkY
    Key: BKWMHKJLXIRTAI-UHFFFAOYSA-N checkY
  • InChI=1/C9H22NO2PS/c1-5-10(6-2)8-9-14-13(4,11)12-7-3/h5-9H2,1-4H3
    Key: BKWMHKJLXIRTAI-UHFFFAOYAU
  • O=P(OCC)(SCCN(CC)CC)C
Properties
Chemical formula
C9H22NO2PS
Molar mass 239.32 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references
Chemical compound

VM (Edemo) is a "V-series" nerve agent closely related to the better-known VX nerve agent.[1]

Like most of the agents in the V-series (with the exception of VX), VM has not been extensively studied outside of military science. Little is known about this chemical compound other than its chemical formula.[1]

It is commonly theorized that the so-called "second-generation" V series agents came from a Cold War era Russian chemical weapons development program. They may have been developed sometime between 1950 and 1990. They have similar lethal dose levels to VX (between 10 and 50 mg) and have similar symptoms and method of action to other nerve agents that act on cholinesterase. The treatment remains the same, but the window for effectively treating second generation V series seizures is shorter. In addition to the standard seizures, some of the second generation V series agents are known to cause comas.[1]

References

  1. ^ a b c Burke, R. (2006). Counter-Terrorism for Emergency Responders (2nd ed.). CRC Press. p. 94. doi:10.1201/9781420009903.fmatt. ISBN 978-0-8493-9923-7.
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Enzyme
(modulators)
ChATTooltip Choline acetyltransferase
  • Inhibitors: 1-(-Benzoylethyl)pyridinium
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AChETooltip Acetylcholinesterase
BChETooltip Butyrylcholinesterase
Transporter
(modulators)
CHTTooltip Choline transporter
VAChTTooltip Vesicular acetylcholine transporter
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(modulators)
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  • SNAP-25Tooltip Synaptosomal-associated protein 25 inactivators: Botulinum toxin (A, C, E)
  • VAMPTooltip Vesicle-associated membrane protein inactivators: Botulinum toxin (B, D, F, G)
Enhancers
See also
Receptor/signaling modulators
Muscarinic acetylcholine receptor modulators
Nicotinic acetylcholine receptor modulators


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