CDP-diacilglicerol—glicerol-3-fosfat 3-fosfatidiltransferaza |
Identifikatori |
EC broj | 2.7.8.5 |
CAS broj | 9068-49-9 |
IntEnz | IntEnz view |
BRENDA | BRENDA entry |
ExPASy | NiceZyme view |
KEGG | KEGG entry |
MetaCyc | metabolic pathway |
PRIAM | profile |
PDB | RCSB PDB PDBe PDBj PDBsum |
Pretraga | PMC | articles | PubMed | articles | NCBI Protein | search | |
CDP-diacilglicerol—glicerol-3-fosfat 3-fosfatidiltransferaza (EC 2.7.8.5, glicerofosfatna fosfatidiltransferaza, 3-fosfatidil-1'-glicerol-3'-fosfatna sintaza, CDPdiacilglicerol:glicerol-3-fosfat fosfatidiltransferaza, citidin 5'-difosfo-1,2-diacil-sn-glicerol (CDPdiglicerid):sn-glicerol-3-fosfat fosfatidiltransferaza, fosfatidilglicerofosfatna sintaza, fosfatidilglicerolfosfatna sintaza, PGP sintaza, CDPdiacilglicerol-sn-glicerol-3-fosfat 3-fosfatidiltransferaza, CDPdiacilglicerol:sn-glicero-3-fosfat fosfatidiltransferaza, glicerol fosfatna fosfatidiltransferaza, glicerol 3-fosfatna fosfatidiltransferaza, fosfatidilglicerol fosfatna sintaza, fosfatidilglicerol fosfatna sintetaza, fosfatidilglicerofosfatna sintetaza, sn-glicerol-3-fosfatna fosfatidiltransferaza) je enzim sa sistematskim imenom CDP-diacilglicerol:sn-glicerol-3-fosfat 3-fosfatidiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-diacilglicerol + sn-glicerol 3-fosfat
CMP + 3(3-sn-fosfatidil)-sn-glicerol 1-fosfat
Reference
- ↑ Bleasdale, J.E. and Johnston, J.M. (1982). „CMP-dependent incorporation of [14C]glycerol 3-phosphate into phosphatidylglycerol and phosphatidylglycerol phosphate by rabbit lung microsomes”. Biochim. Biophys. Acta 710: 377-390. PMID 7074121.
- ↑ Hirabayashi, T. Larson, T.J. and Dowhan, W. (1976). „Membrane-associated phosphatidylglycerophosphate synthetase from Escherichia coli: Purification by substrate affinity chromatography on cytidine 5′-diphospho-1,2-diacyl-sn-glycerol sepharose”. Biochemistry 15: 5205-5211. PMID 793612.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH CDP-diacylglycerol---glycerol-3-phosphate+3-phosphatidyltransferase
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B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6 |