Nukleozid-difosfat kinaza
| Nukleozid-difosfat kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 | |||||||||
| Heksamer nukleozid difosfat kinaze A6 (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.4.6 | ||||||||
| CAS broj | 9026-51-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nukleozid-difosfat kinaza (EC 2.7.4.6, nukleozid 5'-difosfatna kinaza, nukleozid difosfat (UDP) kinaza, nukleozidna difosfokinaza, nukleotid fosfatna kinaza, UDP kinaza, uridin difosfatna kinaza) je enzim sa sistematskim imenom ATP:nukleozid-difosfat fosfotransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + nukleozid difosfat ADP + nukleozid trifosfat
Mnogi nukleozid difosfati mogu da deluju kao akceptori.
Reference
- ↑ Berg, P. and Joklik, W.K. (1954). „Enzymatic phosphorylation of nucleoside diphosphates”. J. Biol. Chem. 210: 657-672. PMID 13211603.
- ↑ Gibson, D.M., Ayengar, P. and Sanadi, D.R. (1956). „Transphosphorylations between nucleoside phosphates”. Biochim. Biophys. Acta 21: 86-91. PMID 13363863.
- ↑ Kirkland, R.J.A. and Turner, J.F. (1959). „Nucleoside diphosphokinase of pea seeds”. Biochem. J. 72: 716-720. PMID 14409347.
- ↑ Krebs, H.A. and Hems, R. (1953). „Some reactions of adenosine and inosine phosphates in animal tissues”. Biochim. Biophys. Acta 12: 172-180. PMID 13115426.
- ↑ Nakamura, H. and Sugino, Y. (1966). „Metabolism of deoxyribonucleotides. 3. Purification and some properties of nucleoside diphosphokinase of calf thymus”. J. Biol. Chem. 241: 4917-4922. PMID 5925862.
- ↑ Ratliff, R.L., Weaver, R.H., Lardy, H.A. and Kuby, S.A. (1964). „Nucleoside triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). I. Isolation of the crystalline enzyme from brewers' yeast”. J. Biol. Chem. 239: 301-309. PMID 14114857.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Spoljašnje veze
- MeSH Nucleoside-diphosphate+kinase
- p
- r
- u
Aktivno mesto • Alosterna regulacija • Mesto vezivanja • Katalitički perfektan enzim • Koenzim • Kofaktor • Kooperativnost • EC broj • Enzimska kataliza • Inhibicija enzima • Enzimska kinetika • Lajnviver–Burk dijagram • Mihaelis–Mentenova kinetika • Spisak enzima
EC1 Oksidoreduktaze/spisak • EC2 Transferaze/spisak • EC3 Hidrolaze/spisak • EC4 Lijaze/spisak • EC5 Izomeraze/spisak • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
